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Article

The Expression of LEP, LEPR, IGF1 and IL10 in Obesity and the Relationship with microRNAs

1 Apr 2014

Abstract excerpt

Obesity is a multifactorial disease, with epigenetic alterations. Have been described modifications in the expression of some microRNAs, and some proteins related to obesity. The objective was to determine and correlate, in obese patients, the gene expression of LEP, LEPR, IGF1, IL10 and of miR-27a, miR-27b, miR-143 and miR-145. RNA was extracted from biopsies of subcutaneous fat, liver and visceral fat of 15...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 24690978
DOI: 10.1371/journal.pone.0093512

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