Article
Modification effect of sex and obesity on the correlation of LEP polymorphisms with leptin levels in Taiwanese obese women.
Molecular genetics & genomic medicine - 1 Mar 2020
Duan De-Min, Jhang Jing-Yi, Wu Semon, Teng Ming-Sheng, Hsu Lung-An, Ko Yu-Lin
Abstract excerpt
BACKGROUND: Obesity has become the main health issue in developed countries as it impacts life expectancy and increases mortality of cerebrovascular or cardiovascular diseases. The leptin is one of the adipokines which presents in the serum in proportion to the amount of adipose tissue and is translated from LEP gene. It involves in energy homeostasis, lipid and glucose metabolisms, modulation of immune systems,...
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