Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Promoter Methylation of LEP and LEPR before and after Bariatric Surgery: A Cross-Sectional Study

1 Jan 2021

Abstract excerpt

INTRODUCTION: DNA methylation constitutes one important epigenetic mechanism that regulates gene expression in human cells. With regard to obesity, bariatric surgery-induced weight loss has been associated with promoter methylation changes in several genes. Hyperleptinemia is a characteristic feature of obesity. The underlying regulating mechanisms have not yet been completely elucidated. METHODS: We investigated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bariatric Surgery and Outcomes
Share to Dietary Effects on Health
Share to Regulation of Appetite and Obesity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33530087
DOI: 10.1159/000511918

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Promoter Methylation of LEP and LEPR before and after Bariatric Surgery: A Cross-Sectional StudyPMID 33530087Read ↗

Leptin and adiponectin DNA methylation levels in adipose tissues and blood cells are associated with BMI, waist girth and LDL-cholesterol levels in severely obese men and womenSemantic proximity Read ↗

Obesity-Related Epigenetic Changes After Bariatric SurgerySemantic proximity Read ↗

Roux-En Y Gastric Bypass Surgery Induces Genome-Wide Promoter-Specific Changes in DNA Methylation in Whole Blood of Obese PatientsSemantic proximity Read ↗

Clinical epigenetics and restoring of metabolic health in severely obese patients undergoing batriatric and metabolic surgerySemantic proximity Read ↗

Human leptin tissue distribution, but not weight loss-dependent change in expression, is associated with methylation of its promoterSemantic proximity Read ↗

Effects of obesity, and of weight loss following bariatric surgery, on methylation of DNA from the rectal mucosa and in cfDNA from bloodSemantic proximity Read ↗

Tissue-specific Leptin promoter DNA methylation is associated with maternal and infant perinatal factors.Semantic proximity Read ↗

Diet‐induced DNA methylation within the hypothalamic arcuate nucleus and dysregulated leptin and insulin signaling in the pathophysiology of obesitySemantic proximity Read ↗

Effects of Roux-en-Y gastric bypass on AGRP, GHRL and POMC genes methylation levels: a 6-months longitudinal study Run title: Gastric bypass and appetite/satiety axisSemantic proximity Read ↗

Duration of breastfeeding is associated with leptin (LEP) DNA methylation profiles and BMI in 10-year-old childrenSemantic proximity Read ↗

DNA Methylation in the Hypothalamic Feeding Center and ObesitySemantic proximity Read ↗

Weight Loss after Gastric Bypass Surgery in Human Obesity Remodels Promoter MethylationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.