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Article

LEP rs7799039, LEPR rs1137101, and ADIPOQ rs2241766 and 1501299 Polymorphisms Are Associated With Obesity and Chemotherapy Response in Mexican Women With Breast Cancer.

Clinical breast cancer - 1 Oct 2017

Méndez-Hernández Alejandra, Gallegos-Arreola Martha Patricia, Moreno-Macías Hortensia, Espinosa Fematt Jorge, Pérez-Morales Rebeca

Abstract excerpt

BACKGROUND: Obesity plays a major role in the pathogenesis of breast cancer. Leptin (LEP) and adiponectin (ADIPOQ) are important in the regulation of adipose tissue. The response to cancer treatment depends on the histological and molecular tumor type, clinical stage, and genetic variability that might promote carcinogenic development. The aim of this study was to investigate the association between...

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Source

Identifiers

PMID: 28416193
DOI: 10.1016/j.clbc.2017.03.010

Genes

LEP
ADIPOQ
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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LEP rs7799039, LEPR rs1137101, and ADIPOQ rs2241766 and 1501299 Polymorphisms Are Associated With Obesity and Chemotherapy Response in Mexican Women With Breast Cancer.PMID 28416193Read ↗

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