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Article

Comparative Genome Sequencing Reveals Within-Host Genetic Changes in Neisseria meningitidis during Invasive Disease.

PloS one - 1 Jan 2017

Klughammer Johanna, Dittrich Marcus, Blom Jochen, Mitesser Vera, Vogel Ulrich, Frosch Matthias, Goesmann Alexander, Müller Tobias, Schoen Christoph

Abstract excerpt

Some members of the physiological human microbiome occasionally cause life-threatening disease even in immunocompetent individuals. A prime example of such a commensal pathogen is Neisseria meningitidis, which normally resides in the human nasopharynx but is also a leading cause of sepsis and epidemic meningitis. Using N. meningitidis as model organism, we tested the hypothesis that virulence of commensal...

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Source

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Identifiers

PMID: 28081260
DOI: 10.1371/journal.pone.0169892
PMCID: PMC5231331

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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