Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in <i>Neisseria meningitidis</i>

Abstract excerpt

Neisseria meningitidis is a leading cause of infectious childhood mortality worldwide. Most research efforts have hitherto focused on disease isolates belonging to only a few hypervirulent clonal lineages. However, up to 10% of the healthy human population is temporarily colonized by genetically diverse strains mostly with little or no pathogenic potential. Currently, little is known about the biology of carriage...

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