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Article

Functional polymorphism in aldehyde dehydrogenase-2 gene associated with risk of tuberculosis.

BMC medical genetics - 2 Apr 2014

Park Seung Kyu, Park Choon-Sik, Lee Hyo-Suk, Park Kyong Soo, Park Byung Lae, Cheong Hyun Sub, Shin Hyoung Doo

Abstract excerpt

BACKGROUND: The well-known genetic polymorphisms in ADH1B(His47Arg) and ALDH2(Glu487Lys) have dramatic effects on the rate of metabolizing alcohol and acetaldehyde. We investigated possible involvement of these functional polymorphisms in other common complex-trait diseases. METHODS: The genetic effects of these two polymorphisms on hepatitis, asthma, type-2 diabetes mellitus (T2DM), and tuberculosis (TB) were...

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Source

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Identifiers

PMID: 24690209
DOI: 10.1186/1471-2350-15-40
PMCID: PMC3975138

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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