Cannabis abuse and age at onset in schizophrenia patients with large, rare copy number variants.

Abstract excerpt

BACKGROUND: Large deletions are found to a greater extent in patients with schizophrenia compared with healthy controls. This study aims to investigate clinical symptomatology and substance abuse rates in patients with large (>500kb), rare (<1% of cohort) deletions and duplications compared with schizophrenia patients in general. METHODS: 633 schizophrenia patients, including 60 with large (>500kb), rare (<1% of...

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