Article
Psychotic patients who used cannabis frequently before illness onset have higher genetic predisposition to schizophrenia than those who did not.
Psychological medicine - 1 Jan 2018
Aas M, Melle I, Bettella F, Djurovic S, Le Hellard S, Bjella T, Ringen P A, Lagerberg T V, Smeland O B, Agartz I, Andreassen O A, Tesli M
Abstract excerpt
BACKGROUND: Schizophrenia (SZ) and bipolar disorder (BD) are heritable, polygenic disorders with shared clinical and genetic components, suggesting a psychosis continuum. Cannabis use is a well-documented environmental risk factor in psychotic disorders. In the current study, we investigated the relationship between SZ genetic load and cannabis use before illness onset in SZ and BD spectrums. Since frequent early...
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