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Article

Increased rare duplication burden genomewide in patients with treatment-resistant schizophrenia

9 Sept 2015

Abstract excerpt

BACKGROUND: A significant number of patients with schizophrenia fail to respond to antipsychotic medication. Although several studies have investigated associated patient characteristics, the emerging findings from genetic studies offer further scope for study. METHOD: In 612 schizophrenia patients with detailed clinical information, common genetic variants indexed by polygenic risk scores, and rare variants...

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Share to Genetic Associations and Epidemiology
Share to Genomic variations and chromosomal abnormalities
Share to Schizophrenia research and treatment

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Identifiers

PMID: 26349998
DOI: 10.1017/s0033291715001701

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