Article
Telomerase Reverse Transcriptase (TERT) Gene Variations and Susceptibility of Colorectal Cancer.
Genetic testing and molecular biomarkers - 1 Dec 2015
Jannuzzi Ayse Tarbin, Karaman Ecem, Oztas Ezgi, Yanar Hakan Teoman, Özhan Gül
Abstract excerpt
AIM: Colorectal cancer is the third most common cause of cancer-related mortality. Previous studies demonstrated increased telomerase activity in colorectal cancer tissue and suggested a prognostic value for patients with colorectal carcinoma. Telomerase reverse transcriptase (TERT), one of the main functional subunits of the telomerase, is an important factor in modulating telomerase activity, telomere length,...
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