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Article

Accuracy of 2-hydroxyglutarate quantification by short-echo proton-MRS at 3 T: a phantom study.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) - 1 Sept 2014

Bertolino Nicola, Marchionni Chiara, Ghielmetti Francesco, Burns Brian, Finocchiaro Gaetano, Anghileri Elena, Bruzzone Maria Grazia, Minati Ludovico

Abstract excerpt

PURPOSE: We set out to investigate the potential confounding effect of variable concentration of N-acetyl-l-aspartate (NAA) and Glutamate (Glu) on measurement of the brain oncometabolite 2-hydroxyglutarate (2HG) using a standard MRS protocol. This issue may arise due to spectral overlap at clinic...

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Identifiers

PMID: 24685182
DOI: 10.1016/j.ejmp.2014.03.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24685182-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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