Article
Simultaneous use of amiodarone influences warfarin maintenance dose but is not associated with adverse events.
Journal of managed care & specialty pharmacy - 1 Apr 2014
Santos Paulo Caleb Junior Lima, Soares Renata Alonso Gadi, Strunz Celia Maria Cassaro, Grinberg Max, Ferreira João Fernando M, Cesar Luiz Antônio Machado, Scanavacca Maurício, Krieger Jose Eduardo, Pereira Alexandre Costa
Abstract excerpt
BACKGROUND: Drug interaction studies selecting patients in a real-life setting are scarce, and most studies to date are characterized by a small sample size. OBJECTIVE: To evaluate the effect of amiodarone on warfarin maintenance dose and adverse events in an anticoagulation cohort from a tertiary cardiovascular service. METHODS: This study recruited 866 patients, and oral anticoagulant therapy was monitored by...
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