Article
Use of pharmacogenetics and clinical factors to predict the maintenance dose of warfarin.
Thrombosis and haemostasis - 1 Jan 2004
Gage Brian F, Eby Charles, Milligan Paul E, Banet Gerald A, Duncan Jill R, McLeod Howard L
Abstract excerpt
Knowledge of pharmacogenetics may help clinicians predict their patients' therapeutic dose of warfarin, thereby decreasing the risk of bleeding during warfarin initiation. Our goal was to use pharmacogenetics to develop an algorithm that uses genetic, clinical, and demographic factors to estimate the warfarin dose a priori. We collected a blood sample, demographic variables, laboratory values, smoking status,...
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