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Article

An algorithm for managing warfarin resistance

1 Dec 2009

Abstract excerpt

Some patients need higher-than-expected doses of warfarin (Coumadin) to get their international normalized ratio (INR) into the therapeutic range. The cause of warfarin resistance can be either acquired (eg, poor compliance, drug interactions, dietary interactions) or hereditary, but the genetic mechanisms of warfarin resistance are not well understood. This review offers an algorithm for the evaluation of...

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PMID: 19952297
DOI: 10.3949/ccjm.76a.09062

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