Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in MicroRNA biosynthesis pathways and binding sites modify ovarian cancer risk, survival, and treatment response.

Cancer research - 1 Dec 2010

Liang Dong, Meyer Larissa, Chang David W, Lin Jie, Pu Xia, Ye Yuanqing, Gu Jian, Wu Xifeng, Lu Karen

Abstract excerpt

MicroRNAs (miRNA) play important roles in tumorigenesis. Genetic variations in miRNA processing genes and miRNA binding sites may affect the biogenesis of miRNA and the regulatory effect of miRNAs to their target genes, hence promoting tumorigenesis. This study analyzed 226 single nucleotide polymorphisms (SNP) in miRNA processing genes and miRNA binding sites in 339 ovarian cancer cases and 349 healthy controls...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biosynthetic Pathways
Share to Kaplan-Meier Estimate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphokines

Share to MicroRNAs

Share to Minor Histocompatibility Antigens

Share to Ovarian Neoplasms

Share to Platelet-Derived Growth Factor

Share to Ribonucleoproteins, Small Nuclear

Source

Open in PubMed Open full text

Identifiers

PMID: 21118967
DOI: 10.1158/0008-5472.CAN-10-0130
PMCID: PMC5373101

Genes

GEMIN4
PDGFC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in MicroRNA biosynthesis pathways and binding sites modify ovarian cancer risk, survival, and treatment response.PMID 21118967Read ↗

Polymorphisms in MicroRNA Binding Sites Predict Colorectal Cancer Survival.Semantic proximity Read ↗

MicroRNA polymorphisms as markers of risk, prognosis and treatment response in hematological malignancies.Semantic proximity Read ↗

Identification of diagnostic and prognostic biomarkers for cancer: Focusing on genetic variations in microRNA regulatory pathways (Review).Semantic proximity Read ↗

Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma.Semantic proximity Read ↗

Polymorphisms in microRNA binding sites of mucin genes as predictors of clinical outcome in colorectal cancer patients.Semantic proximity Read ↗

Genetic polymorphisms and microRNAs: new direction in molecular epidemiology of solid cancer.Semantic proximity Read ↗

Common genetic polymorphisms of microRNA biogenesis pathway genes and breast cancer survival.Semantic proximity Read ↗

LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer.Semantic proximity Read ↗

MicroRNA processing and binding site polymorphisms are not replicated in the Ovarian Cancer Association Consortium.Semantic proximity Read ↗

Role of miRNA gene variants in the susceptibility and pharmacogenetics of colorectal cancer.Semantic proximity Read ↗

Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma.Semantic proximity Read ↗

SNP Regulation of microRNA Expression and Subsequent Colon Cancer Risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.