Article
Competition between Plasmodium falciparum strains in clinical infections during in vitro culture adaptation.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2014
Chen Kexuan, Sun Ling, Lin Yingxue, Fan Qi, Zhao Zhenjun, Hao Mingming, Feng Guohua, Wu Yanrui, Cui Liwang, Yang Zhaoqing
Abstract excerpt
We evaluated the dynamics of parasite populations during in vitro culture adaptation in 15 mixed Plasmodium falciparum infections, which were collected from a hypoendemic area near the China-Myanmar border. Allele types at the msp1 block 2 in the initial clinical samples and during subsequent culture were quantified weekly using a quantitative PCR method. All mixed infections carried two allele types based on the...
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