Article
Chitinases are negative regulators of Francisella novicida biofilms.
PloS one - 1 Jan 2014
Chung Myung-Chul, Dean Scott, Marakasova Ekaterina S, Nwabueze Albert O, van Hoek Monique L
Abstract excerpt
Biofilms, multicellular communities of bacteria, may be an environmental survival and transmission mechanism of Francisella tularensis. Chitinases of F. tularensis ssp. novicida (Fn) have been suggested to regulate biofilm formation on chitin surfaces. However, the underlying mechanisms of how chitinases may regulate biofilm formation are not fully determined. We hypothesized that Fn chitinase modulates bacterial...
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