Article
Strategic siRNA screening approaches to target cancer at the Cancer Research UK Beatson Institute.
Combinatorial chemistry & high throughput screening - 1 May 2014
Shanks Emma J
Abstract excerpt
The RNAi Screening Facility at the Cancer Research UK Beatson Institute combines siRNA genome-wide screening with drug screening coupled with High Content Imaging and fluorescence-based phenotypic assays to target multiple types of cancer. Here, we describe the infrastructure of the Facility and the approaches we utilise. We also share our experiences in running such a facility and developing and executing...
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