Article
A 2-stage genome-wide association study to identify single nucleotide polymorphisms associated with development of erectile dysfunction following radiation therapy for prostate cancer.
International journal of radiation oncology, biology, physics - 1 Jan 2013
Kerns Sarah L, Stock Richard, Stone Nelson, Buckstein Michael, Shao Yongzhao, Campbell Christopher, Rath Lynda, De Ruysscher Dirk, Lammering Guido, Hixson Rosetta, Cesaretti Jamie, Terk Mitchell, Ostrer Harry, Rosenstein Barry S
Abstract excerpt
PURPOSE: To identify single nucleotide polymorphisms (SNPs) associated with development of erectile dysfunction (ED) among prostate cancer patients treated with radiation therapy. METHODS AND MATERIALS: A 2-stage genome-wide association study was performed. Patients were split randomly into a stage I discovery cohort (132 cases, 103 controls) and a stage II replication cohort (128 cases, 102 controls). The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.