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Article

TALENs mediate efficient and heritable mutation of endogenous genes in the marine annelid Platynereis dumerilii.

Genetics - 1 May 2014

Bannister Stephanie, Antonova Olga, Polo Alessandra, Lohs Claudia, Hallay Natalia, Valinciute Agne, Raible Florian, Tessmar-Raible Kristin

Abstract excerpt

Platynereis dumerilii is a marine polychaete and an established model system for studies of evolution and development. Platynereis is also a re-emerging model for studying the molecular basis of circalunar reproductive timing: a biological phenomenon observed in many marine species. While gene expression studies have provided new insight into patterns of gene regulation, a lack of reverse genetic tools has so far...

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Identifiers

PMID: 24653002
DOI: 10.1534/genetics.113.161091
PMCID: PMC4012502

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