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Article

Application of CRISPR/Cas9 Nuclease in Amphioxus Genome Editing.

Genes - 5 Nov 2020

Su Liuru, Shi Chenggang, Huang Xin, Wang Yiquan, Li Guang

Abstract excerpt

The cephalochordate amphioxus is a promising animal model for studying the origin of vertebrates due to its key phylogenetic position among chordates. Although transcription activator-like effector nucleases (TALENs) have been adopted in amphioxus genome editing, its labor-intensive construction of TALEN proteins limits its usage in many laboratories. Here we reported an application of the CRISPR/Cas9 system, a...

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Identifiers

PMID: 33167309
DOI: 10.3390/genes11111311
PMCID: PMC7694359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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