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Article

Genetic polymorphisms in metabolizing enzymes modifying the association between smoking and inflammatory bowel diseases.

Inflammatory bowel diseases - 1 May 2014

Ananthakrishnan Ashwin N, Nguyen Deanna D, Sauk Jenny, Yajnik Vijay, Xavier Ramnik J

Abstract excerpt

BACKGROUND: Cigarette smoking is a well-established environmental risk factor for Crohn's disease (CD) and ulcerative colitis (UC). The exact mechanism of its effect remains unexplained. Genetic polymorphisms in metabolizing enzymes may influence susceptibility to the effect of smoking and shed light on its mechanism of action. METHODS: We used a prospective cohort of patients with CD, UC, and healthy controls....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24651583
DOI: 10.1097/MIB.0000000000000014
PMCID: PMC4113010

Genes

GSTP1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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