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Article

Myeloid-derived suppressor cells contribute to Staphylococcus aureus orthopedic biofilm infection.

Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2014

Heim Cortney E, Vidlak Debbie, Scherr Tyler D, Kozel Jessica A, Holzapfel Melissa, Muirhead David E, Kielian Tammy

Abstract excerpt

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature monocytes and granulocytes that are potent inhibitors of T cell activation. A role for MDSCs in bacterial infections has only recently emerged, and nothing is known about MDSC function in the context of Staphylococcus aureus infection. Because S. aureus biofilms are capable of subverting immune-mediated clearance, we examined...

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Identifiers

PMID: 24646737
DOI: 10.4049/jimmunol.1303408
PMCID: PMC4004612

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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