Article
Phenotype and Function of Myeloid-Derived Suppressor Cells Induced by Porphyromonas gingivalis Infection.
Infection and immunity - 1 Aug 2017
Su Lingkai, Xu Qingan, Zhang Ping, Michalek Suzanne M, Katz Jannet
Abstract excerpt
Porphyromonas gingivalis, a major etiologic agent of periodontitis, has been reported to induce the expansion of myeloid-derived suppressor cells (MDSC); however, little is known regarding the subpopulations of MDSC expanded by P. gingivalis infection. Flow cytometry was used to evaluate bone marrow and spleen cells from mice infected with P. gingivalis and controls for surface expression of CD11b, Ly6G, and...
Topics
- Animals
- Antigens, Ly
- Bacteroidaceae Infections
- Bone Marrow Cells
- CD4-Positive T-Lymphocytes
- Cell Differentiation
- Cell Proliferation
- Cytokines
- Lymphocyte Activation
- Mice
- Myeloid-Derived Suppressor Cells
- Nitric Oxide Synthase Type II
- Osteoclasts
- Peptides