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<i>Staphyloccocus aureus</i> biofilm, in the absence of planktonic bacteria, produces factors that activate counterbalancing inflammatory and immune-suppressive genes in human monocytes

2023-10-06

Abstract excerpt

Staphyloccocus aureus ( S. aureus ) is a major bacterial pathogen in orthopedic periprosthetic joint infection (PJI). S. aureus forms biofilms that promote persistent infection by shielding bacteria from immune cells and inducing an antibiotic-resistant metabolic state. We developed an in vitro system to study S. aureus biofilm interactions with primary human monocytes in the absence of planktonic bacteria. In...

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Literature Corpus work
9bbcf17a-9f6b-54b7-b735-9809b9ed46ab
DOI
10.1101/2023.10.06.561208
Open publication

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<i>Staphyloccocus aureus</i> biofilm, in the absence of planktonic bacteria, produces factors that activate counterbalancing inflammatory and immune-suppressive genes in human monocytesDOI 10.1101/2023.10.06.561208
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