Article
Acetate kinase isozymes confer robustness in acetate metabolism.
PloS one - 1 Jan 2014
Chan Siu Hung Joshua, Nørregaard Lasse, Solem Christian, Jensen Peter Ruhdal
Abstract excerpt
Acetate kinase (ACK) (EC no: 2.7.2.1) interconverts acetyl-phosphate and acetate to either catabolize or synthesize acetyl-CoA dependent on the metabolic requirement. Among all ACK entries available in UniProt, we found that around 45% are multiple ACKs in some organisms including more than 300 species but surprisingly, little work has been done to clarify whether this has any significance. In an attempt to gain...
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