Synthetic RNA recognition motifs that selectively recognize HIV-1 trans-activation response element hairpin RNA.

Abstract excerpt

A multitude of RNA hairpins are directly implicated in human disease. Many of these RNAs are potentially valuable targets for drug discovery and basic research. However, very little is known about the molecular requirements for achieving sequence-selective recognition of a particular RNA sequence and structure. Although a relatively modest number of synthetic small to medium-sized RNA-binding molecules have been...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Base Pairing
• Share to HIV-1
• Share to HIV Infections