Article
Analysis of treatment-resistant schizophrenia and 384 markers from candidate genes.
Pharmacogenetics and genomics - 1 Nov 2012
Teo Celine, Zai Clement, Borlido Carol, Tomasetti Carmine, Strauss John, Shinkai Takahiro, Le Foll Bernard, Wong Albert, Kennedy James L, De Luca Vincenzo
Abstract excerpt
The treatment of patients with schizophrenia who fail to respond to antipsychotics is a major challenge and the proportion of treatment-resistant patients is estimated to be 20 to 40%. There are few genetic association studies that have compared resistant versus non-resistant schizophrenic patients; however, many genetic association studies focusing on antipsychotic response have been published. This contribution...
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