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Article

Influence of neurexin 1 (NRXN1) polymorphisms in clozapine response.

Human psychopharmacology - 1 Nov 2010

Souza Renan P, Meltzer Herbert Y, Lieberman Jeffrey A, Le Foll Bernard, Kennedy James L

Abstract excerpt

Schizophrenia patients show alterations in the synaptic connectivity. However, it remains unknown whether antipsychotic response may be altered depending on the synaptic connectivity. We tested this association using polymorphisms in the neurexin 1 gene (NRXN1). Large NRXN1 deletions have also been associated with schizophrenia. We genotyped four variants in 140 schizophrenia patients assessed prospectively for...

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Source

Identifiers

PMID: 20860064
DOI: 10.1002/hup.1146

Genes

NRXN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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