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Article

Combined effects of genetic variants of the PTEN, AKT1, MDM2 and p53 genes on the risk of nasopharyngeal carcinoma.

PloS one - 1 Jan 2014

Zhang Xiaoai, Chen Xi, Zhai Yun, Cui Ying, Cao Pengbo, Zhang Hongxing, Wu Zhihao, Li Peiyao, Yu Lixa, Xia Xia, He Fuchu, Zhou Gangqiao

Abstract excerpt

Phosphatase and tensin homolog (PTEN), v-akt murine thymoma viral oncogene homolog 1 (AKT1), mouse double minute 2 (MDM2) and p53 play important roles in the development of cancer. We examined whether the single nucleotide polymorphisms (SNPs) in the PTEN, AKT1, MDM2 and p53 genes were related to...

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Source

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Identifiers

PMID: 24632578
DOI: 10.1371/journal.pone.0092135
PMCID: PMC3954877

Genes

AKT1
PTEN
MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24632578-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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