Article
Association between the p73 G4C14-to-A4T14 polymorphism and risk of nasopharyngeal carcinoma: a case-control and family-based study.
Carcinogenesis - 1 Sept 2014
Zhang Xiaoai, Cao Pengbo, Zhai Yun, Zhang Hongxing, Cui Ying, Wu Zhihao, Yuan Xiaoyan, Wang Zhifu, Li Peiyao, Yu Lixa, Xia Xia, He Fuchu, Zhou Gangqiao
Abstract excerpt
p73, a structural and functional homolog of p53, plays an important role in modulating cell cycle control and apoptosis. We examined whether the p73 G4C14-to-A4T14 polymorphism was related to the risk of nasopharyngeal carcinoma (NPC) among Chinese populations. The G4C14-to-A4T14 polymorphism was genotyped in 593 NPC cases and 480 controls, and in 102 NPC trios. Logistic regression analysis and...
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