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Article

Genetic polymorphisms of CCND1 and PTEN in progression of esophageal squamous carcinoma.

Genetics and molecular research : GMR - 13 Dec 2013

Jang Y, Lu S A, Chen Z P, Ma J, Xu C Q, Zhang C Z, Wang J J

Abstract excerpt

Cyclin D1 (CCND1) plays a significant role in G1-S transition of cell cycle, and phosphatase and a tensin homologue (PTEN) negatively regulate cell cycle through phosphatidylinositol 3-kinase (PI3K)/AKT signaling. CCND1 and PTEN genetic polymorphisms might induce susceptibility to the occurrence of esophageal squamous cell carcinoma (ESCC). Three hundred and four ESCC patients and 413 healthy controls from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24391010
DOI: 10.4238/2013.December.13.2

Genes

PTEN
CCND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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