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Article

Relationship of PI3K-Akt/mTOR/AMPK signaling pathway genetic mutation with efficacy and prognosis in nasopharyngeal carcinoma.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 28 Feb 2022

Chen Yanzhu, He Qian, Ma Hongzhi, Zhang Lin, Liu Feng, Han Yaqian

Abstract excerpt

OBJECTIVES: Genetic mutation is one of the important causes for tumor genesis and development, but genetic mutation in nasopharyngeal carcinoma (NPC) has rarely been reported. This study explored the role of phosphatidylinositol 3 kinase-protein kinase B (PI3K-Akt), mammalian target of rapamycin (mTOR), and adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) signaling pathway in the efficacy and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35545406
DOI: 10.11817/j.issn.1672-7347.2022.200821
PMCID: PMC10930525

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