Article
Genome-wide supported variant MIR137 and severe negative symptoms predict membership of an impaired cognitive subtype of schizophrenia.
Molecular psychiatry - 1 Jul 2013
Green M J, Cairns M J, Wu J, Dragovic M, Jablensky A, Tooney P A, Scott R J, Carr V J
Abstract excerpt
Progress in determining the aetiology of schizophrenia (Sz) has arguably been limited by a poorly defined phenotype. We sought to delineate empirically derived cognitive subtypes of Sz to investigate the association of a genetic variant identified in a recent genome-wide association study with specific phenotypic characteristics of Sz. We applied Grade of Membership (GoM) analyses to 617 patients meeting ICD-10...
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