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CSMD1 rs10503253 increases schizophrenia risk in a Tunisian population-group.

L'Encephale - 1 Aug 2024

Mihoub Ons, Ben Chaaben Arij, Boukouaci Wahid, Lajnef Mohamed, Ayari Fayza, El Kefi Hamdi, Ben Ammar Hanen, Abazza Hajer, El Hechmi Zouhair, Guemira Fathi, Leboyer Marion, Tamouza Ryad, Kharrat Maher

Abstract excerpt

OBJECTIVES: Schizophrenia is a complex and chronic neuropsychiatric disorder. Recent genome-wide association studies have identified several at risk genetic variants, including two single nucleotide polymorphisms, namely the rs10503253 and the rs1270942 respectively located in the CSMD1 and the CFB loci. The present case-control study was designed to assess potential associations between the two variants and the...

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PMID: 37748985
DOI: 10.1016/j.encep.2023.08.002

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