Article
HER1 R497K and HER2 I655V polymorphisms are linked to development of breast cancer.
Disease markers - 1 Jan 2013
AbdRaboh Naglaa R, Shehata Hanan H, Ahmed Manal B, Bayoumi Fatehia A
Abstract excerpt
BACKGROUND: Polymorphism of the genes of Human Epidermal growth factor receptor1 (HER1) and receptor2 (HER2) have been reported to be linked to pathogenesis of several malignant tumors but still there is contradiction regarding their association with breast cancer. OBJECTIVE: In this case control study we aimed to analyze the frequency of HER1 R497K (rs 11543848) and HER2 I655V (rs 1136201) Polymorphisms in...
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