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Article

Association of glucocorticoid receptor polymorphisms with clinical and metabolic profiles in polycystic ovary syndrome.

Clinics (Sao Paulo, Brazil) - 1 Mar 2014

Maciel Gustavo A Rosa, Moreira Ricardo P P, Bugano Diogo D G, Hayashida Sylvia A Y, Marcondes José A M, Gomes Larissa G, Mendonça Berenice B, Bachega Tânia A S S, Baracat Edmund C

Abstract excerpt

OBJECTIVES: We aimed to investigate whether glucocorticoid receptor gene polymorphisms are associated with clinical and metabolic profiles in patients with polycystic ovary syndrome. Polycystic ovary syndrome is a complex endocrine disease that affects 5-8% of women and may be associated with metabolic syndrome, which is a risk factor for cardiovascular disease. Cortisol action and dysregulation account for...

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PMID: 24626943
DOI: 10.6061/clinics/2014(03)06
PMCID: PMC3935131

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