Article
Genetic polymorphisms of the glucocorticoid receptor may affect the phenotype of women with anovulatory polycystic ovary syndrome.
Human reproduction (Oxford, England) - 1 Oct 2011
Valkenburg O, Uitterlinden A G, Themmen A P, de Jong F H, Hofman A, Fauser B C J M, Laven J S E
Abstract excerpt
BACKGROUND: Polycystic ovary syndrome (PCOS) is characterized by ovarian dysfunction. The association with obesity and insulin resistance is well established. Steroid hormones play a central role in the regulation of both ovarian function and body composition. This study aims to assess the influence of known functional polymorphisms in genes that are responsible for the production, metabolism and signal...
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