Article
The influence of endocannabinoid receptor 1 gene variations on anthropometric and metabolic parameters of women with polycystic ovary syndrome.
Endokrynologia Polska - 1 Jan 2014
Lenarcik-Kabza Agnieszka, Łaczmański Łukasz, Milewicz Andrzej, Bidzińska-Speichert Bożena, Pawlak Maurycy, Kolackov Katarzyna, Kuliczkowska-Płaksej Justyna, Trzmiel-Bira Anna, Brona Anna
Abstract excerpt
INTRODUCTION: Polycystic ovary syndrome (PCOS) is associated with an increasing number of metabolic comorbidities. About 50% of PCOS patients are obese, and insulin resistance affects up to 70% of these women. The endocannabinoid system contributes to human energy homeostasis. CNR1 is a biological candidate for human obesity and related metabolic disorders. The aim of this study was to determine the relationships...
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