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Article

Associations of genetic risk score with obesity and related traits and the modifying effect of physical activity in a Chinese Han population.

PloS one - 1 Jan 2014

Zhu Jingwen, Loos Ruth J F, Lu Ling, Zong Geng, Gan Wei, Ye Xingwang, Sun Liang, Li Huaixing, Lin Xu

Abstract excerpt

BACKGROUND/OBJECTIVES: Recent large-scale genome-wide association studies have identified multiple loci robustly associated with BMI, predominantly in European ancestry (EA) populations. However, associations of these loci with obesity and related traits have not been well described in Chinese Hans. This study aimed to investigate whether BMI-associated loci are, individually and collectively, associated with...

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Adiposity
Asian People
Body Mass Index
China
Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Regression Analysis

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PMID: 24626232
DOI: 10.1371/journal.pone.0091442
PMCID: PMC3953410

Genes

BDNF
PCSK1
TMEM18

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