Article
Physical activity, smoking, and genetic predisposition to obesity in people from Pakistan: the PROMIS study.
BMC medical genetics - 18 Dec 2015
Ahmad Shafqat, Zhao Wei, Renström Frida, Rasheed Asif, Samuel Maria, Zaidi Mozzam, Shah Nabi, Mallick Nadeem Hayyat, Zaman Khan Shah, Ishaq Mohammad, Rasheed Syed Zahed, Memon Fazal-ur-Rheman, Hanif Bashir, Lakhani Muhammad Shakir, Ahmed Faisal, Kazmi Shahana Urooj, Frossard Philippe, Franks Paul W, Saleheen Danish
Abstract excerpt
BACKGROUND: Multiple genetic variants have been reliably associated with obesity-related traits in Europeans, but little is known about their associations and interactions with lifestyle factors in South Asians. METHODS: In 16,157 Pakistani adults (8232 controls; 7925 diagnosed with myocardial infarction [MI]) enrolled in the PROMIS Study, we tested whether: a) BMI-associated loci, individually or in aggregate...
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