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Article

The role of pharmacogenetics in drug disposition and response of oral glucose-lowering drugs.

Clinical pharmacokinetics - 1 Oct 2013

van Leeuwen N, Swen J J, Guchelaar H-J, 't Hart L M

Abstract excerpt

The primary goal of type 2 diabetes mellitus (T2DM) disease management is improvement of quality of life and prevention of complications. One way to achieve these goals is improving glycemic control by using different types of oral glucose-lowering medications. Currently seven different pharmacological oral glucose-lowering drug classes are available, each with its own mechanism of action and characteristics...

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PMID: 23719679
DOI: 10.1007/s40262-013-0076-3

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