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Article

Varied manifestations of persistent hyperplastic primary vitreous with graded somatic mosaic deletion of a single gene.

Molecular vision - 1 Jan 2014

Mary-Sinclair Michelle N, Wang Xiaofei, Swanson Douglas J, Sung Caroline Y, Mendonca Eneida A, Wroblewski Kristen, Baumer Shannon H, Goldowitz Dan, Jablonski Monica M, Skapek Stephen X

Abstract excerpt

PURPOSE: Persistent hyperplastic primary vitreous (PHPV) represents a developmental eye disease known to have diverse manifestations ranging from a trivial remnant of hyaloid vessels to a dense fibrovascular mass causing lens opacity and retinal detachment. PHPV can be modeled in mice lacking ind...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24623965
PMCID: PMC3945809

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24623965-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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