Article
Ocular abnormalities in mice lacking the Ski proto-oncogene.
Investigative ophthalmology & visual science - 1 Oct 2006
McGannon Peter, Miyazaki Yasumasa, Gupta Pankaj C, Traboulsi Elias I, Colmenares Clemencia
Abstract excerpt
PURPOSE: Persistent hyperplastic primary vitreous (PHPV) is a developmental ocular malformation often associated with additional ocular abnormalities. This study involved a novel mouse model of PHPV, generated by a null mutation of the Ski proto-oncogene, that displays other anterior segment and retinal malformations often found in human cases of PHPV. METHODS: Morphologic and histologic analyses of Ski-/- mice...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
