Article
Extensive individual variation in L1 retrotransposition capability contributes to human genetic diversity.
Proceedings of the National Academy of Sciences of the United States of America - 25 Apr 2006
Seleme Maria del Carmen, Vetter Melissa R, Cordaux Richard, Bastone Laurel, Batzer Mark A, Kazazian Haig H
Abstract excerpt
Despite being scarce in the human genome, active L1 retrotransposons continue to play a significant role in its evolution. Because of their recent expansion, many L1s are not fixed in humans, and, when present, their mobilization potential can vary among individuals. Previously, we showed that th...
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