Article
Inhibition by Cellular Vacuolar ATPase Impairs Human Papillomavirus Uncoating and Infection
11 Mar 2014
Abstract excerpt
Several viruses, including human papillomaviruses, depend on endosomal acidification for successful infection. Hence, the multisubunit enzyme vacuolar ATPase (V-ATPase), which is mainly responsible for endosome acidification in the cell, represents an attractive target for antiviral strategies. In the present study, we show that V-ATPase is required for human papillomavirus (HPV) infection and that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
