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Article

V-ATPase engagement in autophagic processes.

Autophagy - 1 Jun 2011

Mijaljica Dalibor, Prescott Mark, Devenish Rodney J

Abstract excerpt

The proton pumping activity of V-ATPase is responsible for acidification of the lysosome/vacuole. The low lumenal pH of this organelle stimulates the activity of a battery of resident hydrolases responsible for the degradation of various nonselective and selective cargos delivered by autophagic processes. However, the role of V-ATPase in membrane dynamics required for the uptake of autophagic cargo is far from...

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Identifiers

PMID: 21494095
DOI: 10.4161/auto.7.6.15812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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