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Aurintricarboxylic Acid Inhibits the Early Stage of Vaccinia Virus Replication byTargeting both Cellular and Viral Factors

28 Dec 2006

Abstract excerpt

Aurintricarboxylic acid (ATA) has been shown to inhibit the replication of viruses from several different families, including human immunodeficiency virus, vesicular stomatitis virus, and the coronavirus causing severe acute respiratory syndrome. This study characterizes the inhibitory effect of ATA on vaccinia virus replication in HeLa, Huh7, and AD293 cells. Vaccinia virus replication is significantly abrogated...

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PMID: 17192307
DOI: 10.1128/jvi.02531-06

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