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Article

Target enrichment using parallel nanoliter quantitative PCR amplification.

BMC genomics - 10 Mar 2014

De Wilde Bram, Lefever Steve, Dong Wes, Dunne Jude, Husain Syed, Derveaux Stefaan, Hellemans Jan, Vandesompele Jo

Abstract excerpt

BACKGROUND: Next generation targeted resequencing is replacing Sanger sequencing at high pace in routine genetic diagnosis. The need for well validated, high quality enrichment platforms to complement the bench-top next generation sequencing devices is high. RESULTS: We used the WaferGen Smartchip platform to perform highly parallelized PCR based target enrichment for a set of known cancer genes in a well...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24612714
DOI: 10.1186/1471-2164-15-184
PMCID: PMC4234423

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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